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Biomechanics And Medical Devices

Understanding the mechanical properties of soft biological tissues is critical for the development of medical devices to assist or augment human function. I designed an electromagnetic instrument that enables testing of biological samples in the millimeter scale and in controlled environmental conditions. This rig can be used to study the mechanics of soft biological tissue in physiology and disease to ultimately gain a better understanding into how various pathophysiological processes affect the structure and function of organs.

 

I then leverage these insights into human biomechanics to contribute to the development of next-generation medical devices to support organ function and biomechanics. Examples include a 3D-printed soft robotic actuator capable of twisting motion that can be used in hand rehabilitation and a soft robotic sleeve for compression therapy for people with lymphedema or venous insufficiency.

L. Rosalia*, A. Hallou*, L. Cochrane, T. Savin, “A magnetically actuated, optically sensed tensile testing method for mechanical characterisation of soft biological tissues”, Sci. Adv., 4 (2), 2023.  Link

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L. Rosalia, B.A.W. Keong, R.C.H. Yeow, “Geometry-based customization of bending modalities for 3D-printed Soft Pneumatic Actuators” RA-L IEEE, 3 (3489 – 3496), 2018. Link

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L. Rosalia, C. Ozturk, S. Shoar, Y. Fan, G. Malone, F.H. Cheema, C. Conway, R.A. Byrne, G.P. Duffy, A. Malone, E.T. Roche, A. Hameed, “Device-based solutions to improve cardiac physiology and hemodynamics in heart failure with preserved ejection fraction”, JACC: BTS, 6 (9-10), 2021. Link

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Invited Book Chapters

L. Rosalia, M. Saeed, E.T. Roche “Devices that enhance the biomechanics of the failing heart” in Advances in Cardiovascular Technology (eds. J.H. Karimov, K. Fukamachi, M.B.T. Gillinov). Elsevier, 2022. Link

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Peer-Reviewed Conference Proceedings.

L. Rosalia, K.K. Lamberti, M.K. Landry, C.M. Leclerc, F.D. Shuler, N.C. Hanumara, E.T. Roche, “A soft robotic sleeve for compression therapy of the lower limb”, 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2021. 

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